Methylene Blue JFA
Methylthioninium Chloride
CAS: 61-73-4;105504-42-5;121067-62-7;12262-49-6;1341-90-8;167498-52-4;6476-03-5;97130-83-1
Molecular Formula: C16H18ClN3S·3H2O
Methylene Blue JFA - Names and Identifiers
Methylene Blue JFA - Physico-chemical Properties
| Molecular Formula | C16H18ClN3S·3H2O |
| Molar Mass | 373.9 |
| Melting Point | 235℃ |
| Water Solubility | 40 g/L (20℃) |
| Appearance | Dark green crystal |
| Storage Condition | Room Temprature |
| MDL | MFCD00012111 |
| Physical and Chemical Properties | Density 1.00 water-soluble 40g/L (20°C) |
| Use | This product is for scientific research only and shall not be used for other purposes. |
Methylene Blue JFA - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
Methylene Blue JFA - Reference
| Reference Show more | 1. Wang Jiafeng, Gui Zhiping, si Guifu, et al. Preparation, characterization and photocatalytic activity of Ag2CO3 [J]. Journal of Hefei Teachers College, 2016, 34(003):45-48. 2. Mao and Cao Qing Xu peony Huang Meng Zhou Dan Ma Ke pure Zhou Yali he Lei. Preparation technology of V_A Nanoemulsion [J]. Food and Fermentation Industry, 2017, 43(06):232-236. 3. Zhang Tong, Zhang Bo, Li Yu. Decolorization of thiazine dye methylene blue by three white rot fungi [J]. Acta Zoologica Sinica 2018 37(09):137-144. 4. Xiaonan Ma, Xiaolan Han. Experimental study on microleakage of two kinds of pit and fissure sealing materials [D]. CNKI 2014. 5. Wish love, Chen Fan, Liu Shi-Cao, and so on. Adsorption of methylene blue by ultra-fine tourmaline powder [J]. Journal of Wuhan Polytechnic University, 2017(2). 6. Zhao, Yuan, Li, Xiao-Feng. Preparation of naringin ester by enzymatic transesterification and its inhibitory effect on proliferation of HepG2 cells [J]. Modern food science and technology, 2020, v.36;No.249(05):229-236. 7. Zhang He. Research and construction of enzyme biofuel cell and bio-photoelectrochemical system [D]. University of Science and Technology of China, 2020. 8. Tian Yan. Development and application of nano-functional preparations for medicinal plants [D]. Chinese Academy of Agricultural Sciences, 2020. 9. Li Tianyu, Zhang Songshan, Zhang Zhisheng, Zhang Shou, Lei Yuanhua, Xie Peng, Bai Yueyu, Zhang Yang, Sun Baozhong. Variation of edible quality and collagen structure of three kinds of bovine skin during heating [J]. Meat Research, 2020,34(12):18-23. 10. [IF = 3.39] Jianguo Wu et al."Adsorption Thermodynamics and Dynamics of Three Typical Dyes onto Bio-adsorbent Spent Substrate of Pleurotus eryngii."Int J Env Res Pub He. 2019 Jan;16(5):679 11. [IF=1.614] Chenghui Zheng et al."Self-cleaning Bombyx mori silk: room-temperature preparation of anatase nano-TiO2 by the sol-gel method and its application."Color Technol. 2014 Aug;130(4):280-287 12. [IF=9.229] Xin Wang et al."Low-Cost Robust Pressure-Responsive Smart Windows with Dynamic Switchable Transmittance."Acs Appl Mater Inter. 2020;12(13):15695-15702 13. [IF=6.953] Yiming Chen et al."Lightweight and anisotropic cellulose nanofibril/rectorite composite sponges for efficient dye adsorption and selective separation."Int J Biol Macromol. 2022 May;207:130 14. [IF=7.46] Muhammad Shafi et al."Highly sensitive and recyclable surface-enhanced Raman scattering (SERS) substrates based on photocatalytic activity of ZnSe nanowires."Sensor Actuat B- Chem. 2022 Apr;356:131360 15. [IF=15.881] Yiming Chen et al."Liquid Transport and Real-Time Dye Purification via Lotus Petiole-Inspired Long-Range-Ordered Anisotropic Cellulose Nanofibril Aerogels."Acs Nano. 2021;XXXX(XXX):XXX-XXX |
Methylene Blue JFA - Standard
Authoritative Data Verified Data
This product is 3, 7-bis (dimethylamino) phenothiazine-5-locked trihydrate chloride. Calculated as the dried product, the content of C16H18C1N3S shall not be less than 98.5%.
Last Update：2024-01-02 23:10:35
Methylene Blue JFA - Trait
Authoritative Data Verified Data
- This product is dark green, copper light columnar crystal or crystalline powder; Odorless.
- This product is soluble in water or ethanol, dissolved in chloroform.
Last Update：2022-01-01 11:44:02
Methylene Blue JFA - Introduction
Bacterial stain. Serum protein biochemical test with mixed indicator. Prepare exfoliated cell test staining solution. Preparation of alkaline methylene blue staining solution. Redox indicator. Determination of mercury and tin. Reduction titrant.
Last Update：2022-10-16 17:27:02
Methylene Blue JFA - Differential diagnosis
Authoritative Data Verified Data
- take about 10 mg of this product, add 50ml of water to dissolve, and then show dark blue; Take 10ml of solution, add 1 ml of dilute sulfuric acid and 0.LG of zinc powder, the blue color will disappear, and filter, the filtrate was placed in air or 1 drop of hydrogen peroxide solution was added, and the blue color was observed. Another 10ml solution was added, and several drops of potassium iodide solution were added to generate deep blue villous precipitate; take 10ml of the solution and add 0. A few drops of 1 mol/L iodine solution, I .e. dark brown; O.lmol/L sodium thiosulfate solution reappears Blue o
- The infrared absorption spectrum of this product should be consistent with that of the control (Spectrum set 143).
Last Update：2022-01-01 11:44:02
Methylene Blue JFA - Exam
Authoritative Data Verified Data
loss on drying
take this product, dry to constant weight at 105°C, weight loss shall not exceed 18.0% (General rule 0831).
ignition residue
not more than 1.2% (General rule 0841).
zinc salt
take 0.10g of this product, add several drops of sulfuric acid to wet it, Flash, add 5ml of dilute hydrochloric acid and 5ml of water to the residue, boil, add 5ml of ammonia test solution, filter, add 2 drops of Ammonium Sulfide test solution to the filtrate, no precipitation or turbidity should occur.
arsenic salt
take 0.20g of this product, add 0.5g of calcium hydroxide, mix, add a small amount of water, stir evenly, after drying, burn with small fire to make charring, then it should be completely ash by ignition at 600~700°C, and then cooled. Add 5ml of hydrochloric acid and 23ml of water to dissolve the solution, and check according to law (General Principles 0822 first law), and should comply with the regulations (0.001%).
Last Update：2022-01-01 11:44:03
Methylene Blue JFA - Content determination
Authoritative Data Verified Data
take about 0.2g of this product, weigh it accurately, put it in a beaker, add 40ml of water to dissolve it, and heat it to 75°C on a water bath, precision add potassium dichromate titration solution (0.01667mol/L)25ml, shake, at 75°C for 20 minutes, cool, with a vertical melting glass funnel filtration, Beaker and funnel water washing 4 times, 2.5 each time, filter, combine the filtrate and washing solution, shift into a plug Erlenmeyer flask, add water 250ml, sulfuric acid solution (1-5)25ml and potassium iodide test solution 10ml, shake well, use sodium thiosulfate titration solution (0.1 mol/L) titration, to the near end point, add 2ml of starch indicator solution, continue titration to blue disappeared, and the titration result is corrected by blank test. Each 1 ml of potassium dichromate titration solution (0.01667mol/L) corresponds to 10.66mg of C16H18C1N3S.
Last Update：2022-01-01 11:44:03
Methylene Blue JFA - Category
Authoritative Data Verified Data
antidote.
Last Update：2022-01-01 11:44:03
Methylene Blue JFA - Storage
Authoritative Data Verified Data
light shielding, sealed storage.
Last Update：2022-01-01 11:44:04
Methylene Blue JFA - Methylthioninium Chloride Injection
Authoritative Data Verified Data
- This product is a sterilized aqueous solution of methylene blue. Containing methylene blue (C16H18C1N3S.3H20) shall be between 90.0% and 110.05 of the labeled amount.
- 5% glucose is added to this product.
trait
This product is a clear liquid of dark blue.
identification
take this product, according to the methylene blue under the identification (1) test, showed the same reaction.
examination
- the pH value should be 3.5 to 5.0 (General 0631).
- others should comply with the relevant provisions under injection (General 0102).
Content determination
precision take an appropriate amount of this product (equivalent to about 20mg of methylene blue) and dilute it with ethanol to make a solution containing about 2ug per lml, according to UV-visible spectrophotometry (General rule 0401), determine absorbance at the wavelength of 661nm, take appropriate amount of methylene blue reference substance, dilute ethanol is added to dissolve and quantitatively dilute to make a solution containing about 2ug per lml, and the same method is used to determine and calculate, that is, the test quantity contains C16H18C1N3S. The amount of 3 H20.
category
Same as methylene blue.
specification
(l)2ml:20mg (2)5ml:50mg (3)10ml:lOOmg
storage
light shielding, closed storage.
Last Update：2022-01-01 11:44:04
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Product Name: Methylene Blue trihydrate Request for quotationCAS: 亚甲基蓝
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